Ohio State vs. USC prediction: Week 9 college football picks, odds from proven model

The No. 2 Ohio State Buckeyes host the USC Trojans in a Big Ten Conference clash on Saturday, and SportsLine's proven model has released its Week 9 college football picks and best bets. The model simulates every game 10,000 times and has generated over $2,000 in profit for $100 players on top-rated picks. Ohio State enters as a heavy favorite, but USC has shown resilience on the road, making this a compelling matchup for bettors. The model's prediction considers key factors like Ohio State's dominant defense, which allows just 10.3 points per game, and USC's high-powered offense led by quarterback Miller Moss. With kickoff set for 3:30 p.m. ET at Ohio Stadium, the model has identified a strong play on the point spread. Find out which side to back and get the model's score prediction before making your Week 9 college football bets.